*Off-label prescribing is when a licensed provider prescribes a medication for a use other than the one the FDA formally approved. It is legal, common, and guided by clinical judgment and the best available evidence. Talk to your provider about the evidence, benefits, risks, and alternatives. These satements have not been evaluated by the FDA.
GLP-1 receptor agonists, including semaglutide (Wegovy®, Ozempic®, Rybelsus®), tirzepatide (Mounjaro®, Zepbound®), and orforglipron (Foundayo™), have not been approved by the FDA for substance use disorders, cravings, or behavioral compulsions. When used in this way, they are prescribed off-label based on clinical judgment and emerging research.
Providers may also prescribe individualized compounded formulations prepared by licensed 503A pharmacies when clinically appropriate. Compounded medications are not FDA-approved.
Wegovy® and Ozempic® are registered trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are registered trademarks of Eli Lilly and Company. Foundayo™ is a trademark of Eli Lilly and Company. Quel is not affiliated with or endorsed by Novo Nordisk A/S or Eli Lilly and Company.